Research jobs in Basel

What you would do

• Cleaning and disinfecting operational facilities and cage material.
• Caring for and maintaining experimental animals of various species.
• Supporting research groups in animal experiments (drug administration, selection, marking, euthanasia).
• Complying with hygiene regulations (hygiene concept).
• Providing and transferring animals per laboratory personnel instructions.
• Performing internal animal and material transport using company vehicle (Category B).

Skills

What you would do

• Support Good 'x' Practice (GxP) activities in the quality department.
• Manage quality systems.
• Implement operational processes.
• Ensure compliance with Novartis quality standards.

Skills

What you would do

• Develop and implement workflows for culturing, expanding, cryopreserving, and banking immortalised cell lines, iPSCs, hESCs and human primary cells.
• Coordinate with external CROs and the biorepository team to manage routine quality control testing (identity, mycoplasma, sterility, viability, karyotype/genomic stability), review results and maintain documentation for traceability.
• Train and support laboratory scientists in cell culture techniques and biobanking best practices.
• Independently manage licensing compliance, material transfer agreements, and usage restrictions.
• Stay current on emerging cell line authentication, pluripotent cell culture, and biobanking technologies and share findings with internal stakeholders and at conferences.

Skills

What you would do

• Set the strategy, scientific direction, and operating model for laboratory and genomic composite and companion measure development.
• Direct end-to-end development, validation, integration, and delivery of composite measures combining laboratory, genomic, patient-reported, clinician-reported, and digital outcome data.
• Lead research design and execution including validation protocols, analytical methods, technical reports, and troubleshooting strategies.
• Oversee evaluation and validation of laboratory measurement instruments and methods, including installation, operational, and performance qualification documentation.
• Ensure COA data collection, digital-measure data, laboratory operations, and deliverables meet scientific, quality, privacy, and regulatory requirements.
• Lead cross-functional initiatives with therapeutic-area experts, regulators, clients, patient advocacy organizations, and technology partners.

Skills

What you would do

• Performing analyses in basic diagnostics in hematology and coagulation using modern devices.
• Carrying out special analyses in morphology, thalassemia, bone marrow, and coagulation.
• Preparing samples and performing technical/medical validation.
• Ensuring emergency analysis in 24-hour operation.
• Performing technically and qualitatively demanding activities in an accredited laboratory.

Skills

What you would do

• Perform analyses on blood products in quality control.
• Operate the Sysmex XN-1000 hematology analyzer including the blood bank module.
• Plan and execute monthly quality control analyses from BSNW collection sites.
• Plan and implement validation of new materials, devices, and processes.
• Select blood products for regular QC testing.
• Independently record and interpret QC values using the QC tool.

Skills

What you would do

• Prepare samples and reference materials for nitrogen concentration and isotope analysis, including analysis of compounds such as nitrous oxide and nitrate.
• Apply sample-preparation techniques such as microbial conversion methods and gas-purging systems.
• Operate, perform quality control, and carry out basic maintenance of mass spectrometers and associated laboratory instrumentation.
• Maintain laboratory organization and inventory, including ordering consumables, chemicals, and gases.
• Work closely with and assist the laboratory manager and other members of the technical and scientific team.

Skills

What you would do

• Investigate emergent behaviors of biofilm communities that do not occur in isolated bacterial cells.
• Use molecular tools to analyze, manipulate, and perturb biofilms.
• Apply transcriptomics, genetics, and confocal microscopy to study cellular behaviors in biofilms during growth and infection.
• Conduct highly controlled laboratory experiments using microfluidic growth systems for biofilms and stem-cell-derived organoids and bioengineered tissues for infections.
• Develop the exact project with Prof.
• Knut Drescher depending on the student's strengths and interests.

Skills

What you would do

• Developing an individual PhD project within the broader aims of LINC; contributing to the longitudinal collection of quantitative and qualitative data from the participants; recruiting and maintaining contact with research participants across different stages of the longitudinal study; administering language proficiency measures, questionnaires, interviews, diaries, and other research instruments; preparing, managing, documenting, and analysing longitudinal datasets; contributing to quantitative and/or qualitative analyses according to the focus of the doctoral project; participating actively in regular LINC research meetings and collaborative project activities; presenting findings at national and international conferences; preparing research articles for publication in international peer-reviewed journals; contributing to workshops, conferences, dissemination activities, and other events organised within the project.

Skills

What you would do

• Coordinate multi-site clinical research studies including patient scheduling, data collection, and communication with collaborating centers.
• Manage regulatory documentation such as ethics submissions, amendments, and study master files.
• Perform structured annotation and grading of retinal images (OCT, fundus photography, adaptive optics) following standardized protocols.
• Serve as primary liaison for external collaborators and study partners.
• Assist with clinical trial preparation including protocol development, case report form design, and site initiation support.
• Maintain and curate research databases ensuring data integrity and GCP compliance.

Skills

What you would do

• Execute end-to-end workflows for tissue specimens including processing, embedding, sectioning, and staining (IHC, ISH, IF).
• Perform whole slide scanning and digital pathology techniques.
• Perform quality control, routine maintenance, and troubleshooting of histology lab instruments.
• Provide training and support in the use of histology equipment.
• Collaborate with laboratory scientists to optimize tissue-based assays in early drug discovery research projects.
• Stay up to date on new histopathology technologies through scientific literature.

Skills

What you would do

• Handle and monitor experimental mice, including routine health checks, body-weight monitoring, and care of animals under approved water-restriction protocols.
• Support and perform behavioural training and testing of freely moving mice in approach/avoidance and decision-making tasks, including accurate record-keeping.
• Perform stereotaxic surgeries and histological processing, including tissue slicing, immunostaining and fluorescent microscopy.
• Support evolving project needs within the lab through a range of tasks.

Skills

What you would do

• Provide personal, individual patient consultation and advice.
• Perform vaccinations and laboratory analyses.
• Deliver other pharmaceutical services.
• Work across various pharmacy activity areas.
• Handle customer contact and pharmacy operations.
• Progress toward independent work and responsibility during the assistant period.

Skills

What you would do

• Develop and benchmark methods for parameter estimation and uncertainty quantification, from classical optimisation and Bayesian inference to physics-informed neural networks and other machine-learning approaches.
• Build and extend the simulation environment with a focus on performance, scalability and reproducibility.
• Apply methods to real models and data, from imaging-based tissue development models to the digital twin of the hormonal cycle and IVF treatment, in collaboration with modellers, experimentalists and clinical collaborators.
• Publish results and present at international conferences.
• Contribute to open-source software and teaching.

Skills

What you would do

• Work on a jointly agreed-upon scientific, clinical research or global health project under Novartis mentorship.
• Participate in a leadership development program.
• Attend program and training activities.
• Apply state-of-the-art research methodologies learned during the internship within their home institution.

Skills

What you would do

• Support medical professionals in public and private laboratories in Western Switzerland.
• Analyze laboratory infrastructure and identify optimization and improvement potential (up- and cross-selling).
• Maintain long-term customer relationships.
• Support hospital investment projects through stakeholder management with purchasing, hospital IT, and laboratory teams.
• Manage customer orders in cooperation with internal sales, applications, and service teams.
• Update offers and develop services.

Skills

What you would do

• Produce peptides according to established procedures while complying with quality, safety, and laboratory guidelines.
• Execute sample and batch production according to orders, manufacturing instructions, and standard operating procedures.
• Independently execute, monitor, and document synthesis processes.
• Prepare buffers, solutions, and mobile phases.
• Prepare buffers, media, and other solutions upon request from internal customers.
• Maintain complete, accurate, and timely documentation.

Skills

What you would do

• Prepare samples for XRPD, SAXS and complementary analytical techniques, including loading powder samples into thin glass capillaries under controlled conditions, including within a glovebox.
• Accurately weigh powdered materials and prepare microliter-scale liquid samples through pipetting and mixing.
• Participate 1-2 times per month in data collection sessions (beamtime) at synchrotron facilities in Switzerland and Europe.
• Handle, store and ship samples in compliance with operating procedures and complete related documentation.
• Plan and manage beamtime logistics for the team.
• Develop technical solutions for specific sample formats and customized experiments.

Skills

What you would do

• Design, develop, optimize, and execute cell-based assays for compound profiling and mechanism-of-action studies.
• Perform mammalian cell culture, cell-line maintenance, CRISPR/Cas9 gene editing, and generation/isolation/characterization of engineered cell lines.
• Perform DNA/RNA isolation, protein extraction, quantification, and Western blotting.
• Run functional readouts such as proliferation, viability, reporter assays, and cytokine measurements.
• Implement assays using fluorescence, luminescence, TR-FRET, AlphaScreen, or related detection technologies.
• Develop and optimize assay protocols including controls, conditions, and performance parameters, and troubleshoot independently.

Skills

What you would do

• Care for and maintain experimental animals (rodents, zebrafish).
• Independently clean and disinfect animal rooms and cages.
• Ensure compliance with animal protection legislation, hygiene regulations, and internal guidelines.
• Perform breeding care, identification, and biopsy removal.
• Help with electronic recording of animal data.
• Work in SPF barrier facilities and conventional housing.

Skills